The amide bond can be activated for cleavage under mild, neutral conditions by chemical derivatization, a British group has demonstrated (Angew. Chem. Int. Ed., DOI: 10.1002/anie.201107117). Amide ...
This is a scheme of reaction rate acceleration of amide hydrolysis by inclusion in the self-assembled molecular cage. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news ...
Extending or trimming the length of a drug molecule’s carbon backbone by just a couple of atoms can significantly alter its activity, even if nothing else in the structure changes. So reactions that ...
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