For the first time, researchers are able to describe how the dopamine transporter involved in cocaine use operates at the molecular level, which could pave the way to future targeted treatments.

Dopamine, a small molecule derived from the amino acid tyrosine, plays a significant role in regulating multiple essential brain functions, including movement, mood and motivation as well as multiple ...

The dopamine transporter (DAT) is integral to the regulation of synaptic dopamine levels, a process central to the maintenance of normal neurological function. DAT not only mediates the reuptake of ...

Researchers have discovered a new piece in the puzzle of the brain's 'feel good' substance, dopamine. According to one of the researchers behind the new study, the discovery may facilitate the ...

Methamphetamine addiction has long been framed as a story of dopamine gone haywire, with the drug flooding the brain’s reward circuits and rewiring behavior around compulsive use. Emerging work now ...

NEW YORK (July 28, 2008) -- In a first, scientists from Weill Cornell Medical College and Columbia University Medical Center have described the specifics of how brain cells process antidepressant ...

Scientists have long known that cocaine works by latching on to molecular connectors on the surface of brain cells, allowing dopamine, a chemical that promotes feelings of pleasure and reward, to ...

For decades, Parkinson’s disease has been framed as a simple story of dwindling dopamine, a slow erosion of the brain’s movement signal. A wave of new research is now overturning that picture, ...