An effective treatment could be found for one of the most aggressive pediatric cancers, alveolar rhabdomyosarcoma (aRMS). These kinds of tumors, which develop mainly in skeletal muscle, are ...

A protein long implicated in diabetes and obesity may hold the key to treating Alzheimer’s disease by reinvigorating the brain’s immune system. New research suggests that blocking this protein, known ...

A team of scientists has uncovered a critical mechanism that could pave the way for safer and more effective obesity ...

OBJECTIVES: Many patients with type 2 diabetes (T2D) and chronic kidney disease (CKD) experience a delay in treatment or fail to initiate treatment with guideline-recommended angiotensin-converting ...

Researchers at the University of Illinois Chicago have found a small molecule capable of manipulating an immune process that plays an important role in cancers and autoimmune diseases. Their discovery ...

Lymphomas belong to the group of malignant diseases of the immune system and mainly affect the organs of the lymphatic system. Anaplastic large cell lymphoma (ALCL) belongs to the subgroup of ...

Researchers at Queen Mary University of London’s School of Biological and Behavioural Sciences, using the simple fission yeast as a model, have shown that a new target of rapamycin (TOR) inhibitor, ...

The study of urease inhibitors and molecular docking embodies a confluence of advanced synthetic chemistry, computational biology, and structural biochemistry. Urease, a nickel-dependent enzyme ...

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers led by scientists from the DKFZ-Hector Cancer Institute at the University ...

Grapefruit juice is more than a breakfast staple — it’s a potent enzyme inhibitor that can dramatically alter how certain drugs are metabolized. This article explores how a tiny structural difference ...

The immune system must maintain a delicate balance to defend against harmful threats while avoiding excessive inflammation.