Intrathecal drug delivery involves administering analgesic medications directly into the cerebrospinal fluid, thereby achieving targeted pain relief while minimising systemic side effects. This method ...
Real-world use of a CSF circulating tumor cell assay in the diagnosis and management of leptomeningeal metastasis. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract ...
Gene therapy delivered for the first time via lumbar puncture showed promise of benefit in slowing progression of giant axonal neuropathy (GAN) in a phase I clinical trial. The slope of change in ...
Biogen to drive end-to-end development and commercialization of ThecaFlex DRx™, an investigational implantable device for intrathecal delivery of antisense oligonucleotides (ASOs) ThecaFlex DRx™ has ...
Panelists discuss how emerging intrathecal gene therapy for older patients with spinal muscular atrophy (SMA) shows modest efficacy with fewer systemic adverse effects than intravenous administration, ...
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