The tumor microenvironment (TME) is a metabolically dynamic niche where cancer cells and immune cells interact to influence tumor progression and immune ...

This integrated bioinformatic study aimed to investigate potential prognostic candidates in hepatocellular carcinoma (HCC). In the GSE14520, GSE101685, and The Cancer Genome Atlas (TCGA) datasets, ...

Escherichia coli has long served as a model organism and workhorse in the field of metabolic engineering, owing to its rapid growth, well‐characterised genetics and amenability to genetic manipulation ...

There are "costs of life" that mechanical physics cannot calculate. A clear example is the energy required to keep specific biochemical processes active—such as those that make up photosynthesis, ...

CSU is associated with gut microbiota, with metabolic pathways potentially mediating this link, suggesting new research directions. Accurate CSU diagnosis is difficult due to symptom overlap with ...

The field of nutrition and gut microbiome research has increasingly identified the pivotal role of diet in shaping microbial ...

A recent study published in the journal Frontiers in Endocrinology investigated the role of the short-chain dehydrogenase/reductase 42E member 1 (SDR42E1) enzyme in regulating sterol metabolism and ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital, published in Cell, ...