Mitochondria are very special organelles. Known as cellular powerhouses, they can do more than generate energy. They also carry their own tiny genomes, and even have ribosomes that can generate ...

The nuclear envelope (NE) is a dynamic and selective barrier that organizes genome function and nucleocytoplasmic ...

Eukaryotic cells have many specialized complexes and organelles that perform crucial functions. Mitochondria are well known organelles that are critical energy generators, often called the powerhouses ...

Mitochondrial disorders can be devastating, since they affect the energy centers of cells, damaging the brain, heart, kidneys, and muscles. Mothers pass on these ...

For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these mutations cause serious diseases that pass down only through mothers. They ...

In a step toward treating mitochondrial diseases, researchers at the University Medical Center Utrecht and their colleagues have used mitochondrial base editing (mtBE) to successfully edit harmful ...

Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA). This condition can cause symptoms including muscle weakness, ...

Andrew Joseph covers health, medicine, and the biopharma industry in Europe. You can reach Andrew on Signal at drewqjoseph.71. Megan Molteni reports on discoveries from the frontiers of genomic ...

A mitochondrial DNA mutation passed down through the maternal line in some Venezuelan families has been linked to severe brain injury and death in healthy patients undergoing routine anesthesia.