Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from ...

Scientists at the University of California, Santa Cruz (UCSC), used CRISPR to engineer cellular models of embryos that mimic what happens in the first few days after reproductive cells meet. These ...

Multicellularity is one of the most profound phenomena in biology, and relies on the ability of a single cell to reorganize itself into a complex organism. It underpins the diversity in the animal ...

Researchers have identified Nr1h2, a critical transcription factor essential for early embryo development. Their findings enhance our understanding of gene regulation during blastoid formation and ...

Researchers at Vanderbilt University have developed a new embryo culture dish that significantly improves microscope imaging, a longstanding barrier in in‑vitro fertilization (IVF). Traditional 3D ...