Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct structures of the chromatin remodeler SNF2H offering a comprehensive view the ...

A collaborative team led by Bing Li from Shanghai Jiao Tong University School of Medicine published an article titled "BCL7A’s arginine anchor links nucleosome recognition to chromatin remodeling and ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how chromatin ...

From The Bedalov Lab, Human Biology and Translational Science and Therapeutics Divisions Thus, the team began this current study with a scavenger hunt for a nucleosome-modifying enzyme which could ...

Mammalian Toll-like receptors (TLRs) bind to bacterial lipopolysaccharides (LPS) leading to the induction of several cytokine genes that are essential for the inflammatory response. Activation of the ...