EurekAlert!

Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of ...
JSTOR Daily

INTS3 Controls the hSSBl -Mediated DNA Damage Response

Human SSB1 (single-stranded binding protein 1 [hSSB1]) was recently identified as a part of the ataxia telangiectasia mutated (ATM) signaling pathway. To investigate hSSBl function, we performed ...
The Scientist

DNA Polymerase Works in Short Bursts Rather than One Long Stretch

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...
GEN

Protein-Protein Binding Forces Assessed at Single Molecule Level Using Sound Waves and DNA Leashes

Temporary protein-protein bonds are essential for processes including enzymatic reactions, antibody binding, and response to medication. Being able to accurately characterize these bonds is important ...