Dec 24, 2025 · Biologicals are a class of medicines made from living cells taken from plants, animals or bacteria. These cells are use in creating many types of health care products, including vaccines. This …

Good manufacturing practices (GMP) for biological products were first published by WHO in 1992 (1). This current revision reflects subsequent developments that have taken place in science and …

Dec 21, 2020 · This fourth edition of the manual builds on the risk assessment framework introduced in the third edition. A thorough, evidence-based and transparent assessment of the risks allows safety …

Aug 29, 2025 · WHO fact sheet on depression, providing information on prevalence, symptoms, prevention and contributing factors, diagnosis and treatment, and WHO's work in the area.

Oct 4, 2024 · Food and water are the major sources of exposure to both chemical and biological hazards. They impose a substantial health risk to consumers and economic burdens on individuals, …

May 19, 2025 · This year’s International Day for Biological Diversity, on Thursday, 22 May 2025, highlights the inherent connections between people and the natural world through the theme, …

May 22, 2013 · Cell substrates are cells used to manufacture biological products. It is well established that both cell substrates themselves and events linked to cell growth can affect the characteristics …

The WHO sterility testing guidelines are applicable across a wide range of biological medicinal products including vaccines, blood products, biotechnology products, and cell and tissue products.

Oct 16, 2024 · This fact sheet explains when and how menopause occurs, changes that are associated with menopause, related public health challenges and WHO's response.

APIs produced by fermentation and APIs of biological, biotechnological or herbal origin are treated as special cases. The applicant is requested to contact WHO/PQP regarding planned variations to such …